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The Survival of Motor Neuron (SMN) Protein Interacts with the mRNA-Binding Protein HuD and Regulates Localization of Poly(A) mRNA in Primary Motor Neuron Axons

Spinal muscular atrophy (SMA) results from reduced levels of the survival of motor neuron (SMN) protein, which has a well characterized function in spliceosomal small nuclear ribonucleoprotein assembly. Currently, it is not understood how deficiency of a housekeeping protein leads to the selective d...

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Autors principals: Fallini, Claudia, Zhang, Honglai, Su, Yuehang, Silani, Vincenzo, Singer, Robert H., Rossoll, Wilfried, Bassell, Gary J.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070748/
https://ncbi.nlm.nih.gov/pubmed/21389246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3631-10.2011
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