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Spinal muscular atrophy: the role of SMN in axonal mRNA regulation

Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by homozygous mutations or deletions in the survival of motor neuron (SMN1) gene, encoding the ubiquitously expressed SMN protein. SMN associates with different proteins (Gemins 2-8, Unrip) to form a multimeric complex involved in t...

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Bibliografiske detaljer
Main Authors: Fallini, Claudia, Bassell, Gary J., Rossoll, Wilfried
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360984/
https://ncbi.nlm.nih.gov/pubmed/22330725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.01.044
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