Loading...
The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease specifically affecting cortical and spinal motor neurons. Cytoplasmic inclusions containing hyperphosphorylated and ubiquitinated TDP-43 are a pathological hallmark of ALS, and mutations in the gene encoding TDP-43 have been directly...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2012
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406762/ https://ncbi.nlm.nih.gov/pubmed/22641816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds205 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|