Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits

Spinal muscular atrophy (SMA), caused by the deletion of the SMN1 gene, is the leading genetic cause of infant mortality. SMN protein is present at high levels in both axons and growth cones, and loss of its function disrupts axonal extension and pathfinding. SMN is known to associate with the RNA-b...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Akten, Bikem, Kye, Min Jeong, Hao, Le T., Wertz, Mary H., Singh, Sasha, Nie, Duyu, Huang, Jia, Merianda, Tanuja T., Twiss, Jeffery L., Beattie, Christine E., Steen, Judith A. J., Sahin, Mustafa
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121858/
https://ncbi.nlm.nih.gov/pubmed/21652774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104928108
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים