Axonal localization of neuritin/CPG15 mRNA is limited by competition for HuD binding

HuD protein (also known as ELAVL4) has been shown to stabilize mRNAs with AU-rich elements (ARE) in their 3′ untranslated regions (UTRs), including Gap43, which has been linked to axon growth. HuD also binds to neuritin (Nrn1) mRNA, whose 3′UTR contains ARE sequences. Although the Nrn1 3′UTR has bee...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Sci
Päätekijät: Gomes, Cynthia, Lee, Seung Joon, Gardiner, Amy S., Smith, Terika, Sahoo, Pabitra K., Patel, Priyanka, Thames, Elizabeth, Rodriguez, Reycel, Taylor, Ross, Yoo, Soonmoon, Heise, Tilman, Kar, Amar N., Perrone-Bizzozero, Nora, Twiss, Jeffery L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists Ltd 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702053/
https://ncbi.nlm.nih.gov/pubmed/28871047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.201244
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