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The RNA-Binding Protein HuD Regulates Alternative Splicing and Alternative Polyadenylation in the Mouse Neocortex

The neuronal Hu/ELAV-like proteins HuB, HuC and HuD are a class of RNA-binding proteins that are crucial for proper development and maintenance of the nervous system. These proteins bind to AU-rich elements (AREs) in the untranslated regions (3′-UTRs) of target mRNAs regulating mRNA stability, trans...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Sena, Rebecca M., Twiss, Jeffery L., Gardiner, Amy S., Dell’Orco, Michela, Linsenbardt, David N., Perrone-Bizzozero, Nora I.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151252/
https://ncbi.nlm.nih.gov/pubmed/34064652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26102836
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