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Novel recognition motifs and biological functions of the RNA-binding protein HuD revealed by genome-wide identification of its targets

HuD is a neuronal ELAV-like RNA-binding protein (RBP) involved in nervous system development, regeneration, and learning and memory. This protein stabilizes mRNAs by binding to AU-rich instability elements (AREs) in their 3′ unstranslated regions (3′ UTR). To isolate its in vivo targets, messenger r...

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Detalhes bibliográficos
Main Authors: Bolognani, Federico, Contente-Cuomo, Tania, Perrone-Bizzozero, Nora I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800223/
https://ncbi.nlm.nih.gov/pubmed/19846595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp863
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