The Survival of Motor Neuron (SMN) Protein Interacts with the mRNA-Binding Protein HuD and Regulates Localization of Poly(A) mRNA in Primary Motor Neuron Axons

Spinal muscular atrophy (SMA) results from reduced levels of the survival of motor neuron (SMN) protein, which has a well characterized function in spliceosomal small nuclear ribonucleoprotein assembly. Currently, it is not understood how deficiency of a housekeeping protein leads to the selective d...

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Huvudupphovsmän: Fallini, Claudia, Zhang, Honglai, Su, Yuehang, Silani, Vincenzo, Singer, Robert H., Rossoll, Wilfried, Bassell, Gary J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2011
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070748/
https://ncbi.nlm.nih.gov/pubmed/21389246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3631-10.2011
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