Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P(2) to mediate tumour cell permeabilisation

Cationic antimicrobial peptides (CAPs), including taxonomically diverse defensins, are innate defense molecules that display potent antimicrobial and immunomodulatory activities. Specific CAPs have also been shown to possess anticancer activities; however, their mechanisms of action are not well def...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Phan, Thanh Kha, Lay, Fung T., Poon, Ivan K.H., Hinds, Mark G., Kvansakul, Marc, Hulett, Mark D.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811302/
https://ncbi.nlm.nih.gov/pubmed/26657293
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires