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Syntaxin Opening by the MUN Domain Underlies the Function of Munc13 in Synaptic Vesicle Priming
UNC-13-Munc13s play a central function in synaptic vesicle priming through their MUN domains. However, it is unclear whether this function arises from the ability of the MUN domain to mediate the transition from the Munc18-1–closed syntaxin-1 complex to the SNARE complex in vitro. The crystal struct...
Tallennettuna:
| Julkaisussa: | Nat Struct Mol Biol |
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| Päätekijät: | , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4809529/ https://ncbi.nlm.nih.gov/pubmed/26030875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3038 |
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