טוען...
Heterodimerization of Munc13 C(2)A domain with RIM regulates synaptic vesicle docking and priming
The presynaptic active zone protein Munc13 is essential for neurotransmitter release, playing key roles in vesicle docking and priming. Mechanistically, it is thought that the C(2)A domain of Munc13 inhibits the priming function by homodimerization, and that RIM disrupts the autoinhibitory homodimer...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436228/ https://ncbi.nlm.nih.gov/pubmed/28489077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15293 |
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