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Molecular mechanisms of synaptic vesicle priming by Munc13 and Munc18
Munc13 catalyzes the transit of syntaxin from a closed complex with Munc18 into the ternary SNARE complex. Here we report a new function of Munc13, independent of Munc18: it promotes the proper syntaxin / synaptobrevin subconfiguration during assembly of the ternary SNARE complex. In cooperation wit...
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| Izdano u: | Neuron |
|---|---|
| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5747255/ https://ncbi.nlm.nih.gov/pubmed/28772123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.07.004 |
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