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Ca(2+)-triggered synaptic vesicle fusion initiated by release of inhibition

Recent structural and functional studies of the synaptic vesicle fusion machinery suggest an inhibited tripartite complex consisting of neuronal SNAREs, synaptotagmin, and complexin prior to Ca(2+)-triggered synaptic vesicle fusion. We speculate that Ca(2+)-triggered fusion commences with the releas...

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Detalhes bibliográficos
Publicado no:Trends Cell Biol
Main Authors: Brunger, Axel T., Leitz, Jeremy, Zhou, Qiangjun, Choi, Ucheor B., Lai, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056330/
https://ncbi.nlm.nih.gov/pubmed/29706534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2018.03.004
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