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Ca(2+)-triggered synaptic vesicle fusion initiated by release of inhibition

Recent structural and functional studies of the synaptic vesicle fusion machinery suggest an inhibited tripartite complex consisting of neuronal SNAREs, synaptotagmin, and complexin prior to Ca(2+)-triggered synaptic vesicle fusion. We speculate that Ca(2+)-triggered fusion commences with the releas...

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發表在:Trends Cell Biol
Main Authors: Brunger, Axel T., Leitz, Jeremy, Zhou, Qiangjun, Choi, Ucheor B., Lai, Ying
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056330/
https://ncbi.nlm.nih.gov/pubmed/29706534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2018.03.004
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