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Molecular mechanism of the synaptotagmin–SNARE interaction in Ca(2+)-triggered vesicle fusion

In neurons, SNAREs, synaptotagmin, and other factors catalyze Ca(2+)-triggered fusion of vesicles with the plasma membrane. The molecular mechanism of this process remains an enigma, especially regarding the interaction between synaptotagmin and SNAREs. Here we characterized this interaction by sing...

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Detalhes bibliográficos
Main Authors: Vrljic, Marija, Strop, Pavel, Ernst, James A., Sutton, R. Bryan, Chu, Steven, Brunger, Axel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928146/
https://ncbi.nlm.nih.gov/pubmed/20173762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1764
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