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The CASTOR proteins are arginine sensors for the mTORC1 pathway
Amino acids signal to the mTOR complex I (mTORC1) growth pathway through the Rag GTPases. Multiple distinct complexes regulate the Rags, including GATOR1, a GTPase activating protein (GAP), and GATOR2, a positive regulator of unknown molecular function. Arginine stimulation of cells activates mTORC1...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4808398/ https://ncbi.nlm.nih.gov/pubmed/26972053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.035 |
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