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SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway
mTOR complex 1 (mTORC1) regulates cell growth and metabolism in response to multiple environmental cues. Nutrients signal via the Rag guanosine triphosphatases (GTPases) to promote the localization of mTORC1 to the lysosomal surface, its site of activation. We identified SAMTOR, a previously unchara...
Tallennettuna:
| Julkaisussa: | Science |
|---|---|
| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5747364/ https://ncbi.nlm.nih.gov/pubmed/29123071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao3265 |
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