SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway

mTOR complex 1 (mTORC1) regulates cell growth and metabolism in response to multiple environmental cues. Nutrients signal via the Rag guanosine triphosphatases (GTPases) to promote the localization of mTORC1 to the lysosomal surface, its site of activation. We identified SAMTOR, a previously unchara...

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Bibliographic Details
Published in:	Science
Main Authors:	Gu, Xin, Orozco, Jose M., Saxton, Robert A., Condon, Kendall J., Liu, Grace Y., Krawczyk, Patrycja A., Scaria, Sonia M., Harper, J. Wade, Gygi, Steven P., Sabatini, David M.
Format:	Artigo
Language:	Inglês
Published:	2017
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5747364/ https://ncbi.nlm.nih.gov/pubmed/29123071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao3265
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SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway

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