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Dihydroxyacetone phosphate signals glucose availability to mTORC1
The mTOR complex 1 (mTORC1) kinase regulates cell growth by setting the balance between anabolic and catabolic processes. To be active, mTORC1 requires the environmental presence of amino acids and glucose. While a mechanistic understanding of amino acid sensing by mTORC1 is emerging, how glucose ac...
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| Pubblicato in: | Nat Metab |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7995735/ https://ncbi.nlm.nih.gov/pubmed/32719541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-020-0250-5 |
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