Pharmacokinetics-Pharmacodynamics of Tazobactam in Combination with Piperacillin in an In Vitro Infection Model

We have previously demonstrated the pharmacokinetic-pharmacodynamic (PK-PD) index best associated with the efficacy of tazobactam when used in combination with ceftolozane to be the percentage of the dosing interval during which tazobactam concentrations remained above a threshold value (%time>th...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Nicasio, Anthony M., VanScoy, Brian D., Mendes, Rodrigo E., Castanheira, Mariana, Bulik, Catharine C., Okusanya, Olanrewaju O., Bhavnani, Sujata M., Forrest, Alan, Jones, Ronald N., Friedrich, Lawrence V., Steenbergen, Judith N., Ambrose, Paul G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808219/
https://ncbi.nlm.nih.gov/pubmed/26787689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02747-15
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