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Pharmacokinetics-Pharmacodynamics of Tazobactam in Combination with Piperacillin in an In Vitro Infection Model

We have previously demonstrated the pharmacokinetic-pharmacodynamic (PK-PD) index best associated with the efficacy of tazobactam when used in combination with ceftolozane to be the percentage of the dosing interval during which tazobactam concentrations remained above a threshold value (%time>th...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Nicasio, Anthony M., VanScoy, Brian D., Mendes, Rodrigo E., Castanheira, Mariana, Bulik, Catharine C., Okusanya, Olanrewaju O., Bhavnani, Sujata M., Forrest, Alan, Jones, Ronald N., Friedrich, Lawrence V., Steenbergen, Judith N., Ambrose, Paul G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808219/
https://ncbi.nlm.nih.gov/pubmed/26787689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02747-15
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