Pharmacokinetics-Pharmacodynamics of Tazobactam in Combination with Piperacillin in an In Vitro Infection Model

We have previously demonstrated the pharmacokinetic-pharmacodynamic (PK-PD) index best associated with the efficacy of tazobactam when used in combination with ceftolozane to be the percentage of the dosing interval during which tazobactam concentrations remained above a threshold value (%time>th...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Nicasio, Anthony M., VanScoy, Brian D., Mendes, Rodrigo E., Castanheira, Mariana, Bulik, Catharine C., Okusanya, Olanrewaju O., Bhavnani, Sujata M., Forrest, Alan, Jones, Ronald N., Friedrich, Lawrence V., Steenbergen, Judith N., Ambrose, Paul G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808219/
https://ncbi.nlm.nih.gov/pubmed/26787689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02747-15
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