Pharmacokinetics-Pharmacodynamics of Tazobactam in Combination with Cefepime in an In Vitro Infection Model

We previously demonstrated that for tazobactam administered in combination with ceftolozane, the pharmacokinetic-pharmacodynamic (PK-PD) index that best described tazobactam efficacy was the percentage of the dosing interval that tazobactam concentrations were above a threshold (%T>threshold). Us...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: VanScoy, Brian D., Tenero, David, Turner, Simon, Livermore, David M., McCauley, Jennifer, Conde, Haley, Bhavnani, Sujata M., Rubino, Christopher M., Ambrose, Paul G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700300/
https://ncbi.nlm.nih.gov/pubmed/28947475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01052-17
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