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Pharmacokinetics-Pharmacodynamics of CB-618 in Combination with Cefepime, Ceftazidime, Ceftolozane, or Meropenem: the Pharmacological Basis for a Stand-Alone β-Lactamase Inhibitor

A major challenge in treating patients is the selection of the “right” antibiotic regimen. Given that the optimal β-lactam/β-lactamase inhibitor pair is dependent upon the spectrum of β-lactamase enzymes produced and the frequency of resistance to the β-lactamase inhibitor, it might be useful if a s...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ambrose, Paul G., VanScoy, Brian D., Trang, Michael, McCauley-Miller, Jennifer, Conde, Haley, Bhavnani, Sujata M., Alexander, Dylan C., Friedrich, Lawrence V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700306/
https://ncbi.nlm.nih.gov/pubmed/28947474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00630-17
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