Bacterial Replication Rate Modulation in Combination with Antimicrobial Therapy: Turning the Microbe against Itself

A major clinical challenge for treating infectious diseases is the duration of antimicrobial therapy required to eradicate the pathogen. We hypothesized that modulation of the bacterial replication rate in the context of an antimicrobial exposure is coupled with the rate and extent of bactericidal e...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Ambrose, Paul G., VanScoy, Brian, Conde, Haley, McCauley, Jennifer, Rubino, Christopher M., Bhavnani, Sujata M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192140/
https://ncbi.nlm.nih.gov/pubmed/27821440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01605-16
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