Pharmacological Basis of β-Lactamase Inhibitor Therapeutics: Tazobactam in Combination with Ceftolozane

We recently investigated the pharmacokinetics-pharmacodynamics (PK-PD) of tazobactam in combination with ceftolozane against an isogenic CTX-M-15-producing Escherichia coli triplet set, genetically engineered to transcribe different levels of bla(CTX-M-15). The percentage of the dosing interval that...

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Detalhes bibliográficos
Main Authors: VanScoy, Brian, Mendes, Rodrigo E., McCauley, Jennifer, Bhavnani, Sujata M., Bulik, Catharine C., Okusanya, Olanrewaju O., Forrest, Alan, Jones, Ronald N., Friedrich, Lawrence V., Steenbergen, Judith N., Ambrose, Paul G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837916/
https://ncbi.nlm.nih.gov/pubmed/24041895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00656-13
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