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Relationship between Ceftolozane-Tazobactam Exposure and Selection for Pseudomonas aeruginosa Resistance in a Hollow-Fiber Infection Model

It is important to understand the relationship between antibiotic exposure and the selection of drug resistance in the context of therapy exposure. We sought to identify the ceftolozane-tazobactam exposure necessary to prevent the amplification of drug-resistant bacterial subpopulations in a hollow-...

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書誌詳細
主要な著者: VanScoy, Brian D., Mendes, Rodrigo E., Castanheira, Mariana, McCauley, Jennifer, Bhavnani, Sujata M., Jones, Ronald N., Friedrich, Lawrence V., Steenbergen, Judith N., Ambrose, Paul G.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187943/
https://ncbi.nlm.nih.gov/pubmed/25070105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02310-13
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