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Relationship between Fosfomycin Exposure and Amplification of Escherichia coli Subpopulations with Reduced Susceptibility in a Hollow-Fiber Infection Model

Understanding the relationship between antibiotic exposure and amplification of bacterial subpopulations with reduced drug susceptibility over time is important for evaluating the adequacy of dosing regimens. We utilized a hollow-fiber infection model to identify the fosfomycin intravenous dosing re...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: VanScoy, Brian, McCauley, Jennifer, Bhavnani, Sujata M., Ellis-Grosse, Evelyn J., Ambrose, Paul G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4997836/
https://ncbi.nlm.nih.gov/pubmed/27270274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00355-16
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