Pharmacokinetics-Pharmacodynamics of Tazobactam in Combination with Piperacillin in an In Vitro Infection Model

We have previously demonstrated the pharmacokinetic-pharmacodynamic (PK-PD) index best associated with the efficacy of tazobactam when used in combination with ceftolozane to be the percentage of the dosing interval during which tazobactam concentrations remained above a threshold value (%time>th...

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發表在:Antimicrob Agents Chemother
Main Authors: Nicasio, Anthony M., VanScoy, Brian D., Mendes, Rodrigo E., Castanheira, Mariana, Bulik, Catharine C., Okusanya, Olanrewaju O., Bhavnani, Sujata M., Forrest, Alan, Jones, Ronald N., Friedrich, Lawrence V., Steenbergen, Judith N., Ambrose, Paul G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
主題:
Experimental Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808219/
https://ncbi.nlm.nih.gov/pubmed/26787689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02747-15
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