Synthetic α-Hydroxytropolones Inhibit Replication of Wild-Type and Acyclovir-Resistant Herpes Simplex Viruses

Herpes simplex virus 1 (HSV-1) and HSV-2 remain major human pathogens despite the development of anti-HSV therapeutics as some of the first antiviral drugs. Current therapies are incompletely effective and frequently drive the evolution of drug-resistant mutants. We recently determined that certain...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Ireland, Peter J., Tavis, John E., D'Erasmo, Michael P., Hirsch, Danielle R., Murelli, Ryan P., Cadiz, Mark M., Patel, Bindi S., Gupta, Ankit K., Edwards, Tiffany C., Korom, Maria, Moran, Eileen A., Morrison, Lynda A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808205/
https://ncbi.nlm.nih.gov/pubmed/26787704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02675-15
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