Synthetic α-Hydroxytropolones Inhibit Replication of Wild-Type and Acyclovir-Resistant Herpes Simplex Viruses

Herpes simplex virus 1 (HSV-1) and HSV-2 remain major human pathogens despite the development of anti-HSV therapeutics as some of the first antiviral drugs. Current therapies are incompletely effective and frequently drive the evolution of drug-resistant mutants. We recently determined that certain...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Ireland, Peter J., Tavis, John E., D'Erasmo, Michael P., Hirsch, Danielle R., Murelli, Ryan P., Cadiz, Mark M., Patel, Bindi S., Gupta, Ankit K., Edwards, Tiffany C., Korom, Maria, Moran, Eileen A., Morrison, Lynda A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808205/
https://ncbi.nlm.nih.gov/pubmed/26787704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02675-15
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