Synthetic α-Hydroxytropolones Inhibit Replication of Wild-Type and Acyclovir-Resistant Herpes Simplex Viruses

Herpes simplex virus 1 (HSV-1) and HSV-2 remain major human pathogens despite the development of anti-HSV therapeutics as some of the first antiviral drugs. Current therapies are incompletely effective and frequently drive the evolution of drug-resistant mutants. We recently determined that certain...

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發表在:Antimicrob Agents Chemother
Main Authors: Ireland, Peter J., Tavis, John E., D'Erasmo, Michael P., Hirsch, Danielle R., Murelli, Ryan P., Cadiz, Mark M., Patel, Bindi S., Gupta, Ankit K., Edwards, Tiffany C., Korom, Maria, Moran, Eileen A., Morrison, Lynda A.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
主題:
Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808205/
https://ncbi.nlm.nih.gov/pubmed/26787704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02675-15
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