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Fluorous Phase Approach to α-Hydroxytropolone Synthesis

α-Hydroxytropolones (αHTs) are troponoids that demonstrate inhibition against an array of therapeutically significant targets, making them potential drug leads for several human diseases. We have utilized a recently discovered one-pot three-component oxidopyrylium cycloaddition in a solid-supported...

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Bibliografische gegevens
Gepubliceerd in:J Org Chem
Hoofdauteurs: D’Erasmo, Michael P., Murelli, Ryan P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859309/
https://ncbi.nlm.nih.gov/pubmed/29338231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b03032
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