Synthetic α-Hydroxytropolones as Inhibitors of HIV Reverse Transcriptase Ribonuclease H Activity()

HIV Reverse Transcriptase-associated ribonuclease H activity is a promising enzymatic target for drug development that has not been successfully targeted in the clinic. While the α-hydroxytropolone-containing natural products β-thujaplicinol and manicol have emerged as some of the most potent leads...

詳細記述

保存先:
書誌詳細
出版年:Medchemcomm
主要な著者: Murelli, Ryan P., D'Erasmo, Michael P., Hirsch, Danielle R., Meck, Christine, Masaoka, Takashi, Wilson, Jennifer A., Zhang, Baofeng, Pal, Rajat K., Gallicchio, Emilio, Beutler, John A., Le Grice, Stuart F. J.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234084/
https://ncbi.nlm.nih.gov/pubmed/28093576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6MD00238B
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