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Traceless Solid-Phase α-Hydroxytropolone Synthesis
α-Hydroxytropolones are established inhibitors of several therapeutically relevant binuclear metalloenzymes, and thus lead drug targets for various human diseases. We have leveraged a recently-disclosed three-component oxidopyrylium cycloaddition in the first solid-phase synthesis of α-hydroxytropol...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5228208/ https://ncbi.nlm.nih.gov/pubmed/28090282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6MD00237D |
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