Synthetic α-Hydroxytropolones Inhibit Replication of Wild-Type and Acyclovir-Resistant Herpes Simplex Viruses

Herpes simplex virus 1 (HSV-1) and HSV-2 remain major human pathogens despite the development of anti-HSV therapeutics as some of the first antiviral drugs. Current therapies are incompletely effective and frequently drive the evolution of drug-resistant mutants. We recently determined that certain...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ireland, Peter J., Tavis, John E., D'Erasmo, Michael P., Hirsch, Danielle R., Murelli, Ryan P., Cadiz, Mark M., Patel, Bindi S., Gupta, Ankit K., Edwards, Tiffany C., Korom, Maria, Moran, Eileen A., Morrison, Lynda A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808205/
https://ncbi.nlm.nih.gov/pubmed/26787704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02675-15
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