Synthetic α-Hydroxytropolones Inhibit Replication of Wild-Type and Acyclovir-Resistant Herpes Simplex Viruses

Herpes simplex virus 1 (HSV-1) and HSV-2 remain major human pathogens despite the development of anti-HSV therapeutics as some of the first antiviral drugs. Current therapies are incompletely effective and frequently drive the evolution of drug-resistant mutants. We recently determined that certain...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Ireland, Peter J., Tavis, John E., D'Erasmo, Michael P., Hirsch, Danielle R., Murelli, Ryan P., Cadiz, Mark M., Patel, Bindi S., Gupta, Ankit K., Edwards, Tiffany C., Korom, Maria, Moran, Eileen A., Morrison, Lynda A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808205/
https://ncbi.nlm.nih.gov/pubmed/26787704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02675-15
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