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Ceramide Synthase 5 Is Essential to Maintain C(16:0)-Ceramide Pools and Contributes to the Development of Diet-induced Obesity
Ceramides are bioactive sphingolipids, which are composed of sphingoid bases carrying acyl chains of various lengths. Ceramides are synthesized by a family of six ceramide synthases (CerS) in mammals, which produce ceramides with different N-linked acyl chains. Increased ceramide levels are known to...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807283/ https://ncbi.nlm.nih.gov/pubmed/26853464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691212 |
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