Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas

(Dihydro)ceramide synthase 2 (cers2, formerly called lass2) is the most abundantly expressed member of the ceramide synthase gene family, which includes six isoforms in mice. CERS2 activity has been reported to be specific toward very long fatty acid residues (C22–C24). In order to study the biologi...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Imgrund, Silke, Hartmann, Dieter, Farwanah, Hany, Eckhardt, Matthias, Sandhoff, Roger, Degen, Joachim, Gieselmann, Volkmar, Sandhoff, Konrad, Willecke, Klaus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785198/
https://ncbi.nlm.nih.gov/pubmed/19801672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031971
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