Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas

(Dihydro)ceramide synthase 2 (cers2, formerly called lass2) is the most abundantly expressed member of the ceramide synthase gene family, which includes six isoforms in mice. CERS2 activity has been reported to be specific toward very long fatty acid residues (C22–C24). In order to study the biologi...

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Bibliografski detalji
Glavni autori: Imgrund, Silke, Hartmann, Dieter, Farwanah, Hany, Eckhardt, Matthias, Sandhoff, Roger, Degen, Joachim, Gieselmann, Volkmar, Sandhoff, Konrad, Willecke, Klaus
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785198/
https://ncbi.nlm.nih.gov/pubmed/19801672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031971
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