Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas

(Dihydro)ceramide synthase 2 (cers2, formerly called lass2) is the most abundantly expressed member of the ceramide synthase gene family, which includes six isoforms in mice. CERS2 activity has been reported to be specific toward very long fatty acid residues (C22–C24). In order to study the biologi...

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Библиографические подробности
Главные авторы: Imgrund, Silke, Hartmann, Dieter, Farwanah, Hany, Eckhardt, Matthias, Sandhoff, Roger, Degen, Joachim, Gieselmann, Volkmar, Sandhoff, Konrad, Willecke, Klaus
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
Предметы:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785198/
https://ncbi.nlm.nih.gov/pubmed/19801672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031971
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