Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice

Besides bulk amounts of SM, mammalian cells produce small quantities of the SM analog ceramide phosphoethanolamine (CPE). Little is known about the biological role of CPE or enzymes responsible for CPE production. Heterologous expression studies revealed that SM synthase (SMS)2 is a bifunctional enz...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Bickert, Andreas, Ginkel, Christina, Kol, Matthijs, vom Dorp, Katharina, Jastrow, Holger, Degen, Joachim, Jacobs, René L., Vance, Dennis E., Winterhager, Elke, Jiang, Xian-Cheng, Dörmann, Peter, Somerharju, Pentti, Holthuis, Joost C. M., Willecke, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373740/
https://ncbi.nlm.nih.gov/pubmed/25667419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055269
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