Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice

Besides bulk amounts of SM, mammalian cells produce small quantities of the SM analog ceramide phosphoethanolamine (CPE). Little is known about the biological role of CPE or enzymes responsible for CPE production. Heterologous expression studies revealed that SM synthase (SMS)2 is a bifunctional enz...

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Publicado en:J Lipid Res
Autores principales: Bickert, Andreas, Ginkel, Christina, Kol, Matthijs, vom Dorp, Katharina, Jastrow, Holger, Degen, Joachim, Jacobs, René L., Vance, Dennis E., Winterhager, Elke, Jiang, Xian-Cheng, Dörmann, Peter, Somerharju, Pentti, Holthuis, Joost C. M., Willecke, Klaus
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373740/
https://ncbi.nlm.nih.gov/pubmed/25667419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055269
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