Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice

Besides bulk amounts of SM, mammalian cells produce small quantities of the SM analog ceramide phosphoethanolamine (CPE). Little is known about the biological role of CPE or enzymes responsible for CPE production. Heterologous expression studies revealed that SM synthase (SMS)2 is a bifunctional enz...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Lipid Res
Prif Awduron: Bickert, Andreas, Ginkel, Christina, Kol, Matthijs, vom Dorp, Katharina, Jastrow, Holger, Degen, Joachim, Jacobs, René L., Vance, Dennis E., Winterhager, Elke, Jiang, Xian-Cheng, Dörmann, Peter, Somerharju, Pentti, Holthuis, Joost C. M., Willecke, Klaus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2015
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373740/
https://ncbi.nlm.nih.gov/pubmed/25667419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055269
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