Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice

Besides bulk amounts of SM, mammalian cells produce small quantities of the SM analog ceramide phosphoethanolamine (CPE). Little is known about the biological role of CPE or enzymes responsible for CPE production. Heterologous expression studies revealed that SM synthase (SMS)2 is a bifunctional enz...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Lipid Res
Auteurs principaux: Bickert, Andreas, Ginkel, Christina, Kol, Matthijs, vom Dorp, Katharina, Jastrow, Holger, Degen, Joachim, Jacobs, René L., Vance, Dennis E., Winterhager, Elke, Jiang, Xian-Cheng, Dörmann, Peter, Somerharju, Pentti, Holthuis, Joost C. M., Willecke, Klaus
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2015
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373740/
https://ncbi.nlm.nih.gov/pubmed/25667419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055269
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