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Modulation of Ceramide Synthase Activity via Dimerization
Ceramide, the backbone of all sphingolipids, is synthesized by a family of ceramide synthases (CerS) that each use acyl-CoAs of defined chain length for N-acylation of the sphingoid long chain base. CerS mRNA expression and enzymatic activity do not always correlate with the sphingolipid acyl chain...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375526/ https://ncbi.nlm.nih.gov/pubmed/22539345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363580 |
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