CERAMIDE SYNTHASE 1 IS REGULATED BY PROTEASOMAL MEDIATED TURNOVER

Ceramide is an important bioactive lipid, intimately involved in many cellular functions, including the regulation of cell death, and in cancer and chemotherapy. Ceramide is synthesized de novo from sphinganine and acyl CoA via a family of 6 ceramide synthase enzymes, each having a unique preference...

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Bibliographic Details
Main Authors: Sridevi, Priya, Alexander, Hannah, Laviad, Elad L., Pewzner-Jung, Yael, Hannink, Mark, Futerman, Anthony H., Alexander, Stephen
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724657/
https://ncbi.nlm.nih.gov/pubmed/19393694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2009.04.006
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