CERAMIDE SYNTHASE 1 IS REGULATED BY PROTEASOMAL MEDIATED TURNOVER

Ceramide is an important bioactive lipid, intimately involved in many cellular functions, including the regulation of cell death, and in cancer and chemotherapy. Ceramide is synthesized de novo from sphinganine and acyl CoA via a family of 6 ceramide synthase enzymes, each having a unique preference...

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Autori principali: Sridevi, Priya, Alexander, Hannah, Laviad, Elad L., Pewzner-Jung, Yael, Hannink, Mark, Futerman, Anthony H., Alexander, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724657/
https://ncbi.nlm.nih.gov/pubmed/19393694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2009.04.006
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