Modulation of Ceramide Synthase Activity via Dimerization

Ceramide, the backbone of all sphingolipids, is synthesized by a family of ceramide synthases (CerS) that each use acyl-CoAs of defined chain length for N-acylation of the sphingoid long chain base. CerS mRNA expression and enzymatic activity do not always correlate with the sphingolipid acyl chain...

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Bibliografske podrobnosti
Main Authors: Laviad, Elad L., Kelly, Samuel, Merrill, Alfred H., Futerman, Anthony H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375526/
https://ncbi.nlm.nih.gov/pubmed/22539345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363580
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