Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells

BACKGROUND: Regulatory T cells (Treg) are being explored for their tolerance-inducing capabilities. Freezing and banking Treg for future use makes this strategy more clinically applicable. We aimed to devise an improved method of expanding and cryopreserving Treg to maximize yield, purity, and funct...

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Detalhes bibliográficos
Publicado no:Transplant Direct
Main Authors: Weiner, Joshua, Duran-Struuck, Raimon, Zitsman, Jonah, Buhler, Leo, Sondermeijer, Hugo, McMurchy, Alicia N., Levings, Megan K., Sykes, Megan, Griesemer, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Original Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806341/
https://ncbi.nlm.nih.gov/pubmed/27019869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000511
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