Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells

BACKGROUND: Regulatory T cells (Treg) are being explored for their tolerance-inducing capabilities. Freezing and banking Treg for future use makes this strategy more clinically applicable. We aimed to devise an improved method of expanding and cryopreserving Treg to maximize yield, purity, and funct...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Transplant Direct
Main Authors: Weiner, Joshua, Duran-Struuck, Raimon, Zitsman, Jonah, Buhler, Leo, Sondermeijer, Hugo, McMurchy, Alicia N., Levings, Megan K., Sykes, Megan, Griesemer, Adam
Format: Artigo
Jezik:Inglês
Izdano: Lippincott Williams & Wilkins 2015
Teme:
Original Basic Science
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806341/
https://ncbi.nlm.nih.gov/pubmed/27019869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000511
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