Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells

BACKGROUND: Regulatory T cells (Treg) are being explored for their tolerance-inducing capabilities. Freezing and banking Treg for future use makes this strategy more clinically applicable. We aimed to devise an improved method of expanding and cryopreserving Treg to maximize yield, purity, and funct...

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Bibliografiske detaljer
Udgivet i:Transplant Direct
Main Authors: Weiner, Joshua, Duran-Struuck, Raimon, Zitsman, Jonah, Buhler, Leo, Sondermeijer, Hugo, McMurchy, Alicia N., Levings, Megan K., Sykes, Megan, Griesemer, Adam
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2015
Fag:
Original Basic Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806341/
https://ncbi.nlm.nih.gov/pubmed/27019869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000511
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