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Characterization, biology, and expansion of regulatory T cells in the Cynomolgus macaque for pre-clinical studies

Reliable in vitro expansion protocols of regulatory T cells (Tregs) are needed for clinical use. We studied the biology of Mauritian Cynomolgus macaque (MCM) Tregs and developed four in vitro Treg expansion protocols for translational studies. Tregs expanded three-thousand-fold when artificial APCs...

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Detaylı Bibliyografya
Yayımlandı:Am J Transplant
Asıl Yazarlar: Alonso-Guallart, Paula, Zitsman, Jonah S., Stern, Jeffrey, Kofman, Sigal B., Woodland, David, Ho, Siu-Hong, Sondermeijer, Hugo P., Bühler, Leo, Griesemer, Adam, Sykes, Megan, Duran-Struuck, Raimon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658340/
https://ncbi.nlm.nih.gov/pubmed/30768842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15313
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