Characterization, biology, and expansion of regulatory T cells in the Cynomolgus macaque for pre-clinical studies

Reliable in vitro expansion protocols of regulatory T cells (Tregs) are needed for clinical use. We studied the biology of Mauritian Cynomolgus macaque (MCM) Tregs and developed four in vitro Treg expansion protocols for translational studies. Tregs expanded three-thousand-fold when artificial APCs...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Transplant
Prif Awduron: Alonso-Guallart, Paula, Zitsman, Jonah S., Stern, Jeffrey, Kofman, Sigal B., Woodland, David, Ho, Siu-Hong, Sondermeijer, Hugo P., Bühler, Leo, Griesemer, Adam, Sykes, Megan, Duran-Struuck, Raimon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658340/
https://ncbi.nlm.nih.gov/pubmed/30768842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15313
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