Characterization, biology, and expansion of regulatory T cells in the Cynomolgus macaque for pre-clinical studies

Reliable in vitro expansion protocols of regulatory T cells (Tregs) are needed for clinical use. We studied the biology of Mauritian Cynomolgus macaque (MCM) Tregs and developed four in vitro Treg expansion protocols for translational studies. Tregs expanded three-thousand-fold when artificial APCs...

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Veröffentlicht in:Am J Transplant
Hauptverfasser: Alonso-Guallart, Paula, Zitsman, Jonah S., Stern, Jeffrey, Kofman, Sigal B., Woodland, David, Ho, Siu-Hong, Sondermeijer, Hugo P., Bühler, Leo, Griesemer, Adam, Sykes, Megan, Duran-Struuck, Raimon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658340/
https://ncbi.nlm.nih.gov/pubmed/30768842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15313
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