Characterization, biology, and expansion of regulatory T cells in the Cynomolgus macaque for pre-clinical studies

Reliable in vitro expansion protocols of regulatory T cells (Tregs) are needed for clinical use. We studied the biology of Mauritian Cynomolgus macaque (MCM) Tregs and developed four in vitro Treg expansion protocols for translational studies. Tregs expanded three-thousand-fold when artificial APCs...

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Udgivet i:Am J Transplant
Main Authors: Alonso-Guallart, Paula, Zitsman, Jonah S., Stern, Jeffrey, Kofman, Sigal B., Woodland, David, Ho, Siu-Hong, Sondermeijer, Hugo P., Bühler, Leo, Griesemer, Adam, Sykes, Megan, Duran-Struuck, Raimon
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658340/
https://ncbi.nlm.nih.gov/pubmed/30768842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15313
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