Characterization, biology, and expansion of regulatory T cells in the Cynomolgus macaque for pre-clinical studies

Reliable in vitro expansion protocols of regulatory T cells (Tregs) are needed for clinical use. We studied the biology of Mauritian Cynomolgus macaque (MCM) Tregs and developed four in vitro Treg expansion protocols for translational studies. Tregs expanded three-thousand-fold when artificial APCs...

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Bibliografske podrobnosti
izdano v:Am J Transplant
Main Authors: Alonso-Guallart, Paula, Zitsman, Jonah S., Stern, Jeffrey, Kofman, Sigal B., Woodland, David, Ho, Siu-Hong, Sondermeijer, Hugo P., Bühler, Leo, Griesemer, Adam, Sykes, Megan, Duran-Struuck, Raimon
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658340/
https://ncbi.nlm.nih.gov/pubmed/30768842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15313
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