Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells

BACKGROUND: Regulatory T cells (Treg) are being explored for their tolerance-inducing capabilities. Freezing and banking Treg for future use makes this strategy more clinically applicable. We aimed to devise an improved method of expanding and cryopreserving Treg to maximize yield, purity, and funct...

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Dettagli Bibliografici
Pubblicato in:Transplant Direct
Autori principali: Weiner, Joshua, Duran-Struuck, Raimon, Zitsman, Jonah, Buhler, Leo, Sondermeijer, Hugo, McMurchy, Alicia N., Levings, Megan K., Sykes, Megan, Griesemer, Adam
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2015
Soggetti:
Original Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806341/
https://ncbi.nlm.nih.gov/pubmed/27019869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000511
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