Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis

The mTOR complex 1 (mTORC1) and endoplasmic reticulum (ER) stress pathways are critical regulators of intestinal inflammation and colon cancer growth. Sestrins are stress-inducible proteins, which suppress both mTORC1 and ER stress; however, the role of Sestrins in colon physiology and tumorigenesis...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:eLife
Autors principals: Ro, Seung-Hyun, Xue, Xiang, Ramakrishnan, Sadeesh K, Cho, Chun-Seok, Namkoong, Sim, Jang, Insook, Semple, Ian A, Ho, Allison, Park, Hwan-Woo, Shah, Yatrik M, Lee, Jun Hee
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4805551/
https://ncbi.nlm.nih.gov/pubmed/26913956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12204
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars